The next seminar will take place on Monday June 15th, 9:30AM.
Speaker: dr Maciej Jedynak
Title: Synergy of experimentally derived structural and functional connectivities of the human brain.
Over the last few years diffusion Magnetic Resonance Imaging (dMRI) provided invaluable information about structural connectivity of the human brain. Nevertheless, although this technique detects white matter connections, it is blind to their directionality or signal propagation characteristics. Furthermore, dMRI does not inform about functional connectivity, which often is derived from functional Magnetic Resonance Imaging (fMRI) signal correlations. This technique is characterized with timescale of seconds that is too slow to register signal propagation characteristics such as transmission latency or directionality.
In this talk I will introduce the method of functional tractography, which via group analysis derives functional connectivity of the human brain from intracortical stimulations in epileptic patients. These stimulations are characterized with time resolution of miliseconds allowing to determine signal propagation direction and latency. This latency in conjunction with geometry of white matter tracts derived from dMRI allows to estimate speed and directionality of neuronal signal transmission along main anatomical white matter tracts. I will present results from this synergistic study, as well as I will examine mutual consistency of the complementary dMRI and functional tractography modalities.
Meeting ID: 861 4874 1772